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PICTURES OF MICE


27 Pictures of Mice illustrating the phenotype of different alleles of the Mitf locus

 

Microphthalmia heterozygous (OR/vit) mutations

 

Mitf heterozygous compound (Or/vit) mutations

MitfMi-Or/Mitfmi-vit

(3 months old)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

 

Microphthalmia heterozygous (OR/vit) mutations, graying with age

 

Mitf heterozygous compound (Or/vit) mutations

MitfMi-Or/Mitfmi-vit

(graying with age, older behind)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

 

Microphthalmia vit/vit  mutation, graying with age

 

Mitf (vit) mutation

Mitfmi-vit/Mitfmi-vit

(graying with age, older behind)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

 

Microphthalmia vit/vit  mutation, 1 month

 

Mitf (vit) mutation

Mitfmi-vit/Mitfmi-vit

(1 month old)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

 

Microphthalmia mi/vit  mutation, 1  and  3 month old, graying with age

 

Mitf heterozygous compound (mi/vit) mutations

Mitfmi-J/Mitfmi-vit

(1 month, right, and 3 months old, left

graying with age)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

Microphthalmia mi/vit  mutation,  3 month old, graying with age

 

Mitf heterozygous compound (mi/vit) mutations

Mitfmi-J/Mitfmi-vit

(3 months old)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

Microphthalmia mi/mi (front) and mi/vit (behind)  mutations

 

Mitf (mi/mi) and (mi/vit) mutations

Mitfmi-J/Mitfmi-J (front) Mitfmi-J/Mitfmi-vit (back)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

 

Microphthalmia ew/vit  mutations

 

Mitf heterozygous compound (ew/vit) mutations

Mitfmi-ew/Mitfmi-vit

(mouse growing a new coat, dark part is the older coat)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

Microphthalmia rw/vit  mutations, graying with age

 

Mitf heterozygous compound (rw/vit) mutations

Mitfmi-rw/Mitfmi-vit

(graying with age)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

 

Microphthalmia rw/rw mutation

 

Mitf (rw/rw) mutation

Mitfmi-rw/Mitfmi-rw

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

  

Microphthalmia rw/rw mutation

 

Mitf (rw/rw) mutation

Mitfmi-rw/Mitfmi-rw

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

Microphthalmia ws/ws mutation

 

Mitf (ws/ws) mutation

MitfMi-ws/MitfMi-ws (back) MitfMi-ws/Mitf+(front)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

 

Microphthalmia sp/VGA-9  mutations

 

Mitf heterozygous compound (sp/VGA-9) mutations

Mitfmi-sp/Mitfmi-vga9

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

 

Microphthalmia ws/VGA-9  mutations

 

Mitf heterozygous compound (ws/VGA-9) mutations

MitfMi-ws/Mitfmi-vga9

(1 month old)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

 

Microphthalmia sp/sp mutation

 

Mitf (sp/sp) mutation

Mitfmi-sp/Mitfmi-sp

(3 months old)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

 

Microphthalmia mi/sp  mutations

 

Mitf heterozygous compound (mi/sp) mutations

Mitfmi-J/Mitfmi-sp

(3 months old)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

 

Microphthalmia rw/sp  mutations

 

Mitf heterozygous compound (rw/sp) mutations

Mitfmi-rw/Mitfmi-sp

(1 month old)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

 

Microphthalmia vit/sp  mutations

 

Mitf heterozygous compound (vit/sp) mutations

Mitfmi-vit/Mitfmi-sp

(1 month old)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

 

Microphthalmia ew/sp  mutations

 

Mitf heterozygous compound (ew/sp) mutations

Mitfmi-ew/Mitfmi-sp

(1 month old)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

 

Microphthalmia wh/sp  mutations

 

Mitf heterozygous compound (wh/sp) mutations

MitfMi-wh/Mitfmi-sp

(3 months old)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

 

Microphthalmia wh/sp  mutations, reversion clone

 

Mitf heterozygous compound (wh/sp) mutations

MitfMi-wh/Mitfmi-sp

(with a somatic reversion clone, possibly MitfMi-wh to Mitfmi-null, thus resulting in an area of Mitfmi-null/Mitfmi-sp, which, according to known similar phenotypes, would be dark. Comment by Heinz Arnheiter)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

 

Microphthalmia wh/sp  mutations, reversion clone

 

Mitf heterozygous compound (wh/sp) mutations

MitfMi-wh/Mitfmi-sp

(with a somatic reversion clone, possibly MitfMi-wh to Mitfmi-null, thus resulting in an area of Mitfmi-null/Mitfmi-sp, which, according to known similar phenotypes, would be dark. Comment by Heinz Arnheiter)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

 

Microphthalmia b/sp  mutations

 

Mitf heterozygous compound (b/sp) mutations

MitfMi-b/Mitfmi-sp

(3 months old)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

Microphthalmia Or/b  mutations

 

Mitf heterozygous compound (b/Or) mutations

MitfMi-b/MitfMi-Or

(3 months old)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

Microphthalmia Or/b  mutations

 

Mitf heterozygous compound (b/Or) mutations

MitfMi-b/MitfMi-Or

(3 months old)

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

Microphthalmia ws/b  mutations

 

Mitf heterozygous compound (b/ws) mutations

MitfMi-b/MitfMi-ws

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

Microphthalmia mi/Or mutations

 

Mitf heterozygous compound (mi/Or) mutations

Mitfmi-J/MitfMi-Or

 

Genetic background:

C57BL/6J

 

Picture: Lynn Lamoreux

 

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Last modified on April 30, 2009


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