Posts Tagged ‘melanoma’
Meeting and Course: From Melanocyte Development to Melanoma Therapies, Reykjavik, Iceland, June 21-26, 2015Thursday, February 5th, 2015
The European Society for Pigment Cell Research (ESPCR) is pleased to co-sponsor the following two consecutive events on melanocyte and melanoma research that will take place in Iceland next June.
At first, the course From Melanocyte Development to Melanoma Therapies – Basic Science and Clinical Applications, which will be held at the University of Iceland, in Reykjavik, Iceland, June 21-24, 2015. Major advances in basic research of melanoma have lead to novel treatment options that are making a difference for melanoma patients. However, multiple challenges lie ahead and further progress is necessary, particularly with respect to resistance to the novel therapies. This course will teach the basic biology and development of the melanocyte how these cells are transformed into melanoma, and how the disease is diagnosed and treated. A particular emphasis will be on novel therapeutic options and the resistance that arises against the new drugs. This course is organized by: Lionel LARUE – Institut Curie, FR; Eirikur STEINGRIMSSON – University of Iceland, IC; Thorunn RAFNAR – deCODE Genetics, IC; and, Colin GODING – Ludwig Institute, UK
Next, the Conference Melanoma: from basic science to clinical applications, will be held in Harpa, the Concert Hall and Conference Center in Reykjavik, Iceland, June 24-26, 2015. The conference will involve lectures from leaders in melanoma and melanocyte research. Speakers and poster presentations will be selected from abstracts. The conference is designed to stimulate discussions between basic scientists and clinicians and has the ultimate aim of improving therapeutic options in this disease. This meeting is organize by Eirikur Steingrimsson, Lionel Larue, Ze’ev Ronai, Thorunn Rafnar, Caroline Robert, Karl Lewis and René Gonzalez.
The 7th Melanoma Meeting, entitled “Emerging Concepts in Melanoma Biology. Pave the Road to New Therapies” will be held in Nice, France, on June 16-18, 2010.
This meeting is organized by Corine BERTOLOTTO, INSERM U895, Nice; Véronique DELMAS, Institut Curie, Orsay; Robert BALLOTTI, INSERM U895, Nice; Lionel LARUE, Institut Curie, Orsay; Jean-Paul ORTONNE, CHU, Nice; Alain SARASIN, IGR, Villejuif and the meeting pre-program includes, in addition, as invited speakers: Colin GODING, Friedrich BEERMANN, Alain MUAVIEL, Dot BENNETT, Marisol SOENGAS, Daniel PEEPER, Bernard WEHRLE-HALLER, Nathalie LABARRIERE, Richard MARAIS, Caroline ROBERT, Owen SANSOM, Luisa LANFRANCONE, Irwin DAVIDSON, Eirikur STEIMGRIMSSON, Eric GILSON, Marie-Dominique GALIBERT and Keith HOEK.
Registration fee is 70 Euros. Interested participants should contact Robert Ballotti.
No such thing as a safe tan – PCMR replies to sunbed manufacturers. The current issue of Pigment Cell & Melanoma Research (PCMR) features 3 perspectives papers writen by David E. Fisher and collaborators, Marianne Berwick and Dorothy C. Bennett on the dangers of sunbed tanning.
The PCMR WEB site includes an iPod cast interview with Dr David E Fisher on “the dangers of sunbed tanning”.
The three perspective articles are freely accessible from the PCMR website.
UV and pigmentation: molecular mechanisms and social controversies
Thanh-Nga T. Tran, Joshua Schulman, David E. Fisher
Are tanning beds “safe”? Human studies of melanoma
Ultraviolet wavebands and melanoma initiation
Dorothy C. Bennett
PCMR PRESS RELEASE: Thursday September 18, 2008
More than skin deep: There’s no such thing as a ‘safe’ suntan, researchers warn
There may be no such thing as a ‘safe’ tan based on ultraviolet (UV) radiation, according to a series of papers published in the October issue of Pigment Cell & Melanoma Research, the official journal of The International Federation of Pigment Cell Societies (IFPCS) and the Society for Melanoma Research.
The authors of the three review papers – leading researchers in the fields of cell biology, dermatology and epidemiology – have examined the effects on skin of UV radiation, including that from indoor tanning beds. As well as highlighting the need for greater research into this area, they have called for the use of such beds by under-18s to be banned, along with any publicity that claims that tanning beds are safe.
Exposure to UV radiation, for example, from sunbathing or using an indoor tanning bed, affects the skin in a number of ways, including causing DNA damage, photoaging (damage to the skin from chronic exposure to sunlight) and skin cancer. UV radiation is the most ubiquitous carcinogen (cancer-causing agent) for humans, in whom skin is the organ most commonly affected by cancer.
Although more research is required, published data suggest that indoor tanning beds, which are used most by young women, are linked to an increased risk of melanoma (the most dangerous form of skin cancer), and do not support the idea that tanning beds are safe.
In one of three papers in the series published today, Dr David E Fisher, dermatologist and president of the Society of Melanoma Research, and colleagues from the Massachusetts General Hospital, Boston have explored the social issues and molecular mechanisms related to tanning caused by UV exposure. Reviewing published data in the field, the authors report that both tanning and skin cancer seem to begin with the same event – DNA damage caused by UV exposure. This leads them to suggest that a ‘safe’ tan with UV may be a physical impossibility.
The authors conclude: “UVR [ultraviolet radiation] exposure represents one of the most avoidable causes of cancer risk and mortality in man. Whereas genetic and other factors undoubtedly contribute importantly to skin cancer risk, the role of UV is incontrovertible, and efforts to confuse the public, particularly for purposes of economic gain by the indoor tanning industry, should be vigorously combated for the public health.”
The other two papers in the series have been written by Dr Marianne Berwick, an epidemiologist at the University of New Mexico Cancer Research and Treatment Centre, and Dr Dorothy C Bennett, a dermatologist at the Division of Basic Medical Sciences, St George’s, University of London, London, UK. The three papers and a related podcast with Dr Fisher can be accessed for free online at http://www.pigment.org/.
Skin cancer is the most common malignancy in the US; the American Academy of Dermatology reports than one American dies every 62 minutes from melanoma. The WHO estimated that, in the year 2000, up to 71 000 deaths worldwide were attributed to excessive UV exposure.